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Difference between blood and lymph - Biology


It is a red-colored fluid and connective tissue which flows inside the blood vessels. It is the main component of the circulatory system. Its cells are quite distinct from other connective tissues both in structure and functions. The extracellular material in the blood is a fluid devoid of fibers. Fluid outside the cell is generally called extracellular fluid. Blood is heavier than water. Blood travels throughout the body in a circular motion. The extracellular material in the blood is a straw color liquid called plasma. It is a slightly alkaline, aqueous fluid having 7.4 pH. Constituents having characteristic forms, float in the plasma. They are collectively called formed elements of blood. They include blood cells and blood platelets.

Blood cells are of two types- erythrocytes and leukocytes. The total RBC count averages 5 million and 4.5 million in adult males and females respectively. A healthy person has 12-16 grams of hemoglobin per 100 ml of blood. An abnormal rise in RBC count is called Polycythemia. Anemia is caused due to deficiency of folic acid, vitamin B12, and hemoglobin. Leukocytes are devoid of hemoglobin and are consequently colorless. They are of two main types- granulocytes and granulocytes. Granulocytes are of two types- lymphocytes and monocytes. The total leukocyte count is 6000-8000/mm3 of blood.

The blood is composed of blood cells, blood platelets, and plasma. Plasma contains plasma proteins like serum albumin, serum globulin, prothrombin, and fibrinogen. Tissues may utilize plasma proteins for forming their cellular proteins. Plasma proteins help in maintaining blood pH by neutralizing strong acid and base hence they are called acid-base buffers. Plasma forms 55-60% by volume of blood. Plasma proteins constitute 7-8% of plasma. Various organic/ inorganic components, salts, nutrients, and gases are found dissolved in the blood.

Blood is red due to the presence of hemoglobin. It is a protein pigment that contains iron. One molecule of hemoglobin carries oxygen molecules from the lungs during respiration. Blood contributes to homeostasis by transporting oxygen, carbon dioxide, nutrients, and hormones to and from your body’s cells. It helps regulate body pH and temperature and protects against disease through phagocytosis and the production of antibodies. Blood transports various substances, helps regulate several life processes and affords protection against disease. For all of its similarities in origin, composition, and functions, blood is as unique from one person to another as are skin, bone, and hair. Health-care professionals routinely examine and analyze its differences through various blood tests when trying to determine the cause of different diseases. The branch of science concerned with the study of blood, blood-forming tissues, and the disorders associated with them is hematology.


The lymphatic system consists of a colorless fluid called lymph. This lymph is a part of the lymphatic system. It flows only in one direction inside the lymphatic vessels. The lymphatic system along with lymph assists in bodily defense mechanisms. Lymph contains less amount of fibrinogen; hence it does not clot easily. Most components of blood plasma filter through blood capillary walls to form interstitial fluid. The interstitial fluid becomes lymph after passing into lymphatic vessels. The function of lymphatic vessels is to drain excess interstitial fluid from tissue spaces. It is then returned to the blood. Lymph is responsible for the transportation of lipid and lipid-soluble proteins i.e., Vitamin A, D, E, K absorbed from the gastrointestinal tract. Lacteals are specialized lymphatic capillaries in the small intestine. They carry dietary lipids into lymphatic vessels and finally into the blood. The presence of these lipids is the reason why lymph drains from the small intestine appear to be creamy white. These are known as Chyle. Elsewhere, lymph is a clear, pale-yellow fluid.

Difference between blood and lymph

Blood Lymph
Blood is a red-colored fluid connective tissue. Lymph is a colorless fluid connective tissue lacking RBC.
The process of formation of blood takes place in the bone marrow. Formation of lymph takes place by the fluid which seeps out of thin walls of capillaries into the body’s tissues.
It is a part of the circulatory system It is a part of the lymphatic and immune system
Blood consists of plasma, WBCs, RBCs, and platelets. Plasma contains proteins, calcium, and phosphorus. Lymph consists of WBC, a few platelets, and lymph plasma that do not contain proteins.
Blood vessels contain blood flowing at a fast rate. Lymphatic vessels contain lymph which moves at a slow rate.
Due to the presence of fibrinogen, it clots quickly. As clotting factors are few, hence less fibrinogen is present; as a result clotting of lymph is delayed.
Blood moves in a circular motion throughout the body. Lymph moves in a single direction only





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