Thyroid Hormones Types and Their Function: CBSE Class 12 Biology

BY Team Aakash Byjus

The thyroid gland is an endocrine gland in the shape of a butterfly, located over the neck.

Thyroid Gland

It is present on the front side of the neck. It is located below the Adam's apple, along the front of the trachea.

Location and Structure of Thyroid Gland

Thyroid gland comprises two side lobes connected by a bridge(isthmus) in the Centre.

The thyroid gland secretes various kinds of hormones.  These include as follows: T0, T1, T2, T3, T4 and Calcitonin.

Hormones Secreted by the Thyroid Gland

T0, T1, T2 Hormones are the by-products formed during synthesis of thyroid hormone. They don’t act on thyroid hormone receptors.

T0, T1, T2 Hormones

It is a highly active hormone. Involves natural regulation, which is generally unhelpful to do. It is central in the digestive and metabolic functions and oversees bone health.

Triiodothyronine ( T3 or L3,5,3’)

It is a more stable form. It is an inactive prohormone. It plays a major role in digestion, brain functioning, muscle functioning, heart functioning, etc.

Thyroxine  (T4 or L-3, 5,3’,5’) 

Calcitonin hormone regulates the levels of Calcium and Phosphates in blood.

Calcitonin Hormone

Calcitonin hormone is opposing the actions of parathyroid hormone secreted by parathyroid glands, which acts to reduce Calcium and Phosphates levels in the blood.

Hypothyroidism disease is caused when the thyroid gland fails to secrete enough Hormone.

Diseases caused by low and excessive levels of thyroid hormones:

Hypothyroidism:

Cold sensitivity, fatigue, dry skin, constipation, and unexpected weight gain.

Symptoms

Treatment

Treatment consists of thyroid hormone replacement.

Hyperthyroidism

Hyperthyroidism disease is caused when the thyroid gland secretes excess hormones.

Unexpected weight loss, irregular heartbeat, sweating and irritability.

Symptoms

Treatment includes radioactive iodine, medication and sometimes surgery.

Treatment